Computational Genomics Evolutionary Medicine

At the Jeong Lab, we examine genome structure and epigenetic regulation across species and cell types to better understand human evolution, aging, and neurological disorders. We combine comparative genomics with long-read sequencing and single-cell multi-omics data to resolve complex genomic regions and characterize their regulatory activity. We develop computational models to identify complex patterns and infer how genomic and epigenomic variation influences gene regulation.